Stephen C Cannon Selected Research

Hypokalemic Periodic Paralysis (Periodic Paralysis, Hypokalemic)

1/2022	Voltage-dependent Ca2+ release is impaired in hypokalemic periodic paralysis caused by CaV1.1-R528H but not by NaV1.4-R669H.
11/2021	Gating pore currents occur in CaV1.1 domain III mutants associated with HypoPP.
1/2018	Stac3 enhances expression of human CaV1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels.
8/2014	Disrupted coupling of gating charge displacement to Na+ current activation for DIIS4 mutations in hypokalemic periodic paralysis.
3/2013	Bumetanide prevents transient decreases in muscle force in murine hypokalemic periodic paralysis.
12/2012	A calcium channel mutant mouse model of hypokalemic periodic paralysis.
10/2011	A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis.
5/2011	Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia.
6/2010	Voltage-sensor mutations in channelopathies of skeletal muscle.
10/2008	Gating pore currents in DIIS4 mutations of NaV1.4 associated with periodic paralysis: saturation of ion flux and implications for disease pathogenesis.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Stephen C Cannon Research Topics

Disease

11	Hypokalemic Periodic Paralysis (Periodic Paralysis, Hypokalemic) 01/2022 - 07/2007
11	Channelopathies 01/2022 - 07/2002
11	Myotonia 01/2020 - 07/2002
11	Paralysis (Palsy) 01/2020 - 08/2002
3	Muscular Diseases (Myopathy) 01/2019 - 01/2016
2	Epilepsy (Aura) 09/2019 - 01/2010
2	Myotonic Dystrophy (Dystrophia Myotonica) 12/2004 - 07/2002
1	Myoclonic Epilepsies (Myoclonic Encephalopathy) 01/2021
1	Brain Diseases (Brain Disorder) 01/2021
1	Arthrogryposis 01/2020
1	Bronchial Spasm 01/2020
1	Seizures (Absence Seizure) 09/2019
1	Acidosis 01/2019
1	Malignant Hyperthermia 01/2017
1	Muscle Hypotonia (Hypotonia) 03/2016
1	Myotonia Congenita (Thomsen Disease) 03/2014
1	Rare Diseases (Rare Disease) 03/2014
1	Muscle Weakness 12/2013
1	Hyperkalemic Periodic Paralysis 03/2013
1	Limb-Girdle Muscular Dystrophies (Limb-Girdle Muscular Dystrophy) 10/2011
1	Limb-girdle muscular dystrophy type 2H 10/2011
1	Bardet-Biedl Syndrome (Syndrome, Bardet-Biedl) 10/2011
1	Dystonia (Limb Dystonia) 07/2004
1	Dystonia 12 07/2004

Drug/Important Bio-Agent (IBA)

16	Sodium Channels (Sodium Channel)IBA 01/2022 - 06/2005
8	Arginine (L-Arginine)FDA Link 01/2022 - 07/2007
7	Calcium Channels (Calcium Channel)IBA 01/2022 - 06/2010
4	PotassiumIBA 11/2021 - 04/2008
4	SodiumIBA 01/2021 - 06/2010
4	Chloride Channels (Chloride Channel)IBA 04/2015 - 07/2002
4	ChloridesIBA 03/2014 - 07/2002
4	Ion Channels (Ion Channel)IBA 06/2010 - 08/2002
3	Proteins (Proteins, Gene)FDA Link 09/2019 - 12/2004
2	Protons (Proton)IBA 01/2018 - 07/2007
2	CalciumIBA 01/2018 - 12/2012
2	Potassium Channels (Potassium Channel)IBA 01/2018 - 04/2015
2	Bumetanide (Bumex)FDA LinkGeneric 12/2013 - 03/2013
2	Protein Isoforms (Isoforms)IBA 10/2008 - 07/2007
2	RNA Precursors (Precursor, mRNA)IBA 12/2004 - 07/2002
1	Indicators and Reagents (Reagents)IBA 01/2022
1	Oregon Green 488 carboxylic acidIBA 01/2022
1	L-Type Calcium Channels (Dihydropyridine Receptor)IBA 11/2021
1	Carbamazepine (Tegretol)FDA LinkGeneric 01/2020
1	Lysine (L-Lysine)FDA Link 01/2020
1	MagnesiumIBA 01/2017
1	Dantrolene (Dantrium)FDA LinkGeneric 01/2017
1	Insulin (Novolin)FDA Link 12/2013
1	Glucose (Dextrose)FDA LinkGeneric 12/2013
1	Cysteine (L-Cysteine)FDA Link 07/2013
1	Tripartite Motif ProteinsIBA 10/2011
1	Voltage-Gated Sodium ChannelsIBA 03/2008
1	Ligand-Gated Ion ChannelsIBA 01/2006
1	Messenger RNA (mRNA)IBA 12/2004
1	Adenosine Triphosphatases (ATPase)IBA 07/2004
1	RNA (Ribonucleic Acid)IBA 07/2002

Therapy/Procedure

2	Therapeutics 01/2020 - 12/2013
1	Drug Therapy (Chemotherapy) 09/2019
1	Transcutaneous Electric Nerve Stimulation (TENS) 01/2019